ABSTRACT
A case report of a patient with treated Non-Hodgkin Lymphoma is presented. In his usual tomographic control patient was requested a PET-CT scan to supplement prior study that showed a metabo-lically active focus on the left adductor muscle without evident tomographic correlation. Lesion underwent both a soft tissue ultrasound study and a directed biopsy, the latter being positive for secondary infiltration by lymphoma. This case has demonstrated the usefulness of applying complementary techniques in the management of these lesions, mainly of PET-CT scans in the study of unusual sites of spread. This combined medical imaging technique allows accurate lesion localization, which in turn permits performance of a subsequent directed study.
Se presenta un caso clínico de paciente con linfoma no Hodgkin tratado; en control tomográfico habitual se le solicitó PET-CT para complementar su estudio, que demuestra un foco metabólicamente activo en el espesor de músculo aductor izquierdo sin traducción tomográfica evidente. La lesión fue estudiada con ultrasonografia de partes blandas y biopsia dirigida, que resultó positiva para infiltración secundaria por linfoma. Este caso demuestra la utilidad de las técnicas complementarias en el manejo de estos pacientes, en especial la utilidad del PET-CT en el estudio de sitios inhabituales de diseminación. En este examen existe la posibilidad de identificar con precisión la localización de las lesiones mediante la TC complementaria, lo que permite efectuar posteriormente el estudio dirigido.
Subject(s)
Humans , Male , Middle Aged , Lymphoma, Non-Hodgkin , Lymphoma, Non-Hodgkin/pathology , Muscles , Muscles/pathology , Neoplasm Metastasis , Positron-Emission Tomography , Tomography, X-Ray ComputedSubject(s)
Humans , Male , Middle Aged , Diverticulitis/complications , Gases , Portal Vein/pathology , Portal Vein , Tomography, X-Ray ComputedABSTRACT
El tumor estromal gastrointestinal (GIST) representa menos del 3 por ciento de las neoplasias gastrointestinales; sin embargo, es el tumor mesenquimatico mas frecuente del tracto digestivo. GIST se define por la expresión de un receptor de factor de crecimiento de tirosina kinasa, CD117, lo que lo diferencia de los otros tumores mesenquimáticos como leiomiomas, leio-miosarcomas, leiomioblastomas y tumores neurogénicos, que no expresan esta proteína. 70-80 por ciento de los GISTs son benignos, localizándose la mayoría en estomago e intestino delgado (> 90 por ciento). Pueden originarse también de cualquier porción del tracto digestivo, así como del mesenterio, omento y retroperitoneo. GISTs malignos son generalmente de gran tamaño (> a 5 cm), con índice mitótico alto, y puede metastizar a hígado y peritoneo. Hallazgos sugerentes a la tomografía computada (TC) son: masa exofitica que se origina de la pared del estomago o intestino, bien delimitada, que puede presentar hemorragia, necrosis o componente quístico, raramente asociada a obstrucción. El tratamiento es la resección quirúrgica. Se han descrito buenos resultados con inhibidor de tirosina kinasa STI571.
Subject(s)
Humans , Gastrointestinal Neoplasms , Stromal Cells , Diagnosis, DifferentialSubject(s)
Humans , Female , Adult , Lipomatosis, Multiple Symmetrical , Carpal Bones , Wrist/abnormalities , WristABSTRACT
Background: There is evidence to postulate that undernotification is the reason for the great decrease in the reported incidence of hydatidosis in Chile. Aim: To develop and propose a method to assess the notification of transmissible diseases, based on observed lethality and hospital discharges. Material and methods: Human hydatidosis in the period 1985-1994 was used as a model to develop the method. Official reports and mortality were analyzed first, determining the first lethality rate. A second lethality rate was calculated based on hospital discharges and a third, based on all Chilean surgical series published in the last two decades. Adjusting official notification of lethality to the true lethality according to surgical series, the number of unreported cases was calculated and the true incidence of hydatidosis was calculated, summing these cases to the official notification. Results: According to this method, the real rates of human hydatidosis in the period 1985-1994, would fluctuate between 6.5 and 11.4 per 100,000. This figure is four times higher than the official notification in the analysed period. Conclusions: The correction of under notification based on hospital discharges, with or without correction for repeated hospital admissions, or real mortality of surgical series gave similar results, suggesting that both methods are correct